• br Introduction Cardiovascular diseases rank

  2018-10-24

  

  Introduction Cardiovascular diseases rank the first in cause of death, which account for ∼30% of all deaths worldwide (Mozaffarian et al., 2015). Unlike robust cardiac regeneration observed in adult zebrafish and embryonic and neonatal mice (Porrello et al., 2011; Poss et al., 2002; Sturzu et al.

• br Discussion br Experimental Procedures br Author

  2018-10-24

  

  Discussion Experimental Procedures Author Contributions Acknowledgments We thank members of the Azrieli Center for Stem Cells and Genetic Research at the Hebrew University for their contribution, and especially Mordecai Peretz for assistance with the figures, and Ido Sagi for critical re

• br Introduction Anthracycline antibiotics including doxorubi

  2018-10-24

  

  Introduction Anthracycline antibiotics, including doxorubicin (Dox), remain the cornerstone of treatment for a variety of malignancies (Arcamone et al., 2000). Nonetheless, they are well known to cause dose-dependent, progressive myocardial damage known as anthracycline-induced cardiomyopathy (AI

• br Results br Discussion There is considerable

  2018-10-24

  

  Results Discussion There is considerable interest in developing high-throughput technologies for microscale analysis and screening of both undifferentiated and differentiated human stem/progenitor populations to aid drug screening and toxicity analysis (Bhatia and Ingber, 2014; El-Ali et al.,

• br Introduction Mesenchymal stem stromal cells MSCs are

  2018-10-24

  

  Introduction Mesenchymal stem/stromal pgc-1α inhibitor (MSCs) are an excellent biological source for bone regenerative therapies, tissue engineering, and treatment of post-menopausal osteoporosis (Murphy et al., 2013; Steinert et al., 2012). Ex vivo expansion of autologous bone marrow stromal ce

• In this study we seek to examine

  2018-10-24

  

  In this study, we seek to examine the efficacy of using adeno-associated virus 9 (AAV9) to express NEUROD1 in infected cortical and striatal astrocytes through a systemic intravascular route. Previous work suggests that intravascular introduction of AAV9 is able to specifically infect the astrocytic

• crf1 Our study has focused on charged particle

  2018-10-24

  

  Our study has focused on charged particle fluxes in a small neighborhood of the plane of symmetry, which allowed approximately calculating the spatial distribution of the field structure; for this we employed the well-known expansion in powers of the small quantity z: The study in the degree of a

• Many species of dolphins produce long frequency

  2018-10-24

  

  Many species of dolphins produce long frequency-modulated (FM) acoustic signals containing a large number of harmonics that occur at n-tuples of the fundamental frequency (n is an integer). Such signals have come to be called whistles because this is how humans perceive them. The repertoire of cont

• One possible reason why lasing characteristics deteriorate a

  2018-10-24

  

  One possible reason why lasing characteristics deteriorate at high injection levels in materials with a low band gap may be non-radiative Auger recombination, which can have a resonant character under certain conditions, leading to a marked increase in the recombination rate [3]. Studying the recomb

• br Methods br Results br Discussion In this

  2018-10-24

  

  Methods Results Discussion In this paper we have drawn on Extended Normalisation Process Theory to evaluate the delivery of a complex intervention – the Strengthening Families Programme 10–14. We have used the theory as a framework to understand how the interplay between the intervention an

• This discussion goes back to the phenomenon

  2018-10-23

  

  This discussion goes back to the phenomenon occurred in Holland in the 1960s, when the discovery of large natural gas deposits had diverse effects on resource allocation in the economy. If, on the one hand, exports provided an increase in income, on the other, the currency appreciation, due to the e

• My focus is not on the actual

  2018-10-23

  

  My focus is not on the actual (endogenous) decrease in corruption generated by the separation of middlemen. This decrease may be computed, in expected terms, for different technologies and contractual arrangements – i.e., separation or those of regulators. For the purpose of the present paper, it i

• Despite the success of targeted therapies

  2018-10-23

  

  Despite the success of targeted therapies, many genomic alterations are considered “undruggable”. One such example is the above-mentioned t(11,14)(q13, 32) translocation, which increases the expression of cyclin D1 (). Another example of such an undruggable target is CD22ΔE12, described in a researc

• Our results provide a fundamental insight into

  2018-10-23

  

  Our results provide a fundamental insight into the nature of primary varicose vein disease. A strong influence of genotypes at MTHFR c.677C>T and c.1298A>C on the morphological specification of primary varicose veins and progression towards complicated disease is suggested. The results provide clues

• find more info In our previous study we conducted a comprehe

  2018-10-23

  

  In our previous study, we conducted a comprehensive proteomic analysis to identify candidate biomarkers in OSCC (Wang et al., 2008). Expression levels of 52 proteins in OSCC tumor tissues were significantly different from those in normal tissues (Wang et al., 2009). One of these proteins was PA28γ.

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