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In contrast with hydrophilic metabolites
2018-10-23
In contrast with hydrophilic metabolites, the lipid profile was relatively uniform among samples and did not highlight their heterogeneity. The levels CEs with long-chain highly desaturated fatty acids were elevated in tumors; this was consistent with the notion that clear cell RCCs are rich in CEs
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Many researchers have conducted experimental studies
2018-10-23
Many researchers have conducted experimental studies on mitochondrial dysfunction in sepsis. When Zheng et al. searched PubMed databases and Web of Science databases from 1950 to January 2014, 121 studies were identified involving the use of mitochondrial therapy in sepsis (Zheng et al., 2015). Acco
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There are several potential molecular pathways via which hyp
2018-10-23
There are several potential molecular pathways via which hypercholesterolemia-induced chronic metabolic abnormalities might affect circadian profiles, as follows. First, the DNA-binding activity of the BMAL1 and CLOCK heterodimer is regulated by the redox state of nicotinamide adenine dinucleotide (
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Previously it was reported that
2018-10-23
Previously it was reported that the release of both Tim-3 and galectin-9 depends on PKCα and proteolysis (Chabot et al., 2002). Our results confirmed these findings. PMA treatments induced PKCα activation, which activated exocytosis of Tim-3 and galectin-9 as well as their mTOR-dependent production
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br Experimental design materials and methods br Acknowledgme
2018-10-23
Experimental design, materials and methods Acknowledgments The authors would like to acknowledge the generous support of Dr. Elena Hidalgo (Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain) for kindly providing the yeast strain, Dr. Ranjan K. Nandy (Di
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The NMR analysis of the reaction media of
2018-10-23
The NMR analysis of the reaction media of β-CHO and t-BuOOH oxidation, revealed the formation of order AZD8055 6. The results obtained from 1D 1H, COSY and 1D selective NOESY experiments of the aqueous media of reaction, allowed the 1H NMR characterization of the molecule. Fig. 1 shows the structure
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br Data Reported data represents the
2018-10-23
Data Reported data represents the observed association between use of injectable insulin preceding breast cancer and the growth factor profiles at the time of cancer diagnosis in women with diabetes mellitus (Table 1). Data in Table 2 includes the observed correlations between growth factors stra
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Binary logistic regression Enter method shows that the
2018-10-22
Binary logistic regression (Enter method) shows that the presence of lipodermosclerosis has a significant positive prognostic significance in healing of chronic VUs (p Discussion Venous ulcerations occur in 1% of the human population. They are frequently found in persons older than 65 years. The
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On the other hand Zimmermann
2018-10-22
On the other hand, Zimmermann studied transition metal carbonyl complexes as blast enhancers and boosters for hollow charge explosives in order to improve burning [34]. The carbonyls tested consist of Cr(CO)6, Mo(CO)6, W(CO)6, Fe(CO)5, Fe2(CO)9, and Fe3(CO)12[34]. Mechanism of action Fuel-air ex
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En el campo del feminismo
2018-10-22
En el campo del feminismo estructuralista, Patricia Hill Collins (2000) fue la primera en hablar de la interseccionalidad como un paradigma; sin embargo, fue Ange Marie Hancock (2007) quien propuso una formalización de este paradigma, entendido como un conjunto que engloba hydroxylase la vez teoría
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NS-398 To estimate the model we use static and dynamic estim
2018-10-22
To estimate the model, we use static and dynamic estimation techniques. The static estimation is the fixed effect OLS estimator to capture bank-specific differences while the dynamic estimation is the GMM estimator to capture dynamic adjustments to bank profitability. We consider dynamic adjustments
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Introduction The notorious frontispiece of
2018-10-22
Introduction The notorious frontispiece of the 1905 edition of A History of Architecture on the Comparative Method, written by the two Banister Fletchers, father and son, and entitled “The Tree of Architecture,” illustrated various style of European architecture emerging out of a trunk labeled “Gre
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The challenge of developing adaptive responsive low energy a
2018-10-22
The challenge of developing adaptive, responsive low-energy architecture requires new knowledge about the complex and dynamic interaction between envelope geometry and optimisation of performance metrics (Hudson, 2008). In this paper, we present the results of a building envelope tessellation study
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In this work the study of the
2018-10-22
In this work, the study of the spatial distribution of temperatures in two test trpv1 was based on the concept of the experimental typical day, which represents a specific climate condition according to the Dynamic Climate approach. The possibility of adopting this approach in a short time contribut
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Introduction There is increasing interest in exploring
2018-10-22
Introduction There is increasing interest in exploring complex freeform shapes in contemporary architectural and design practice. Frank Gehry (Lindsey, 2001) and Zaha Hadid (Jodidio, 2009) are prime examples of pioneering avant-garde designers who have incorporated freeform shapes into their design
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