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Interestingly Prominin is found in other
2018-11-08
Interestingly, Prominin1 is found in other adult stem cell populations, such as those in the hematopoietic system and small intestine (Snippert et al., 2009; Zhu et al., 2009) and is a marker of tumor-initiating pitavastatin in several cancers (Neuzil et al., 2007). It was originally discovered in
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Third the ability to form calcified material due
2018-11-08
Third, the ability to form calcified material due to the overexpression of TMSB4X may depend on the cell type. The formation of calcified material was induced in the TMSB4X-transfected squamous epithelial cell-derived carcinoma cell lines, MISK81-5 and HSC-3 cells. However, no capacity for calcifica
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thiostrepton To identify the label retaining cells
2018-11-08
To identify the label-retaining thiostrepton within the myocardium, BrdU was administrated and the intensity of the BrdU signal was examined after a prolonged chasing period (Urbanek et al., 2006). As expected, the number of bright BrdU-CSCs in the atria decreased rapidly after chasing while the nu
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These conclusions rest mainly on three experimental facts a
2018-11-08
These conclusions rest mainly on three experimental facts: a model of myocardial injury with patent coronary circulation to test the spontaneous regenerative capacity of eCSCs; in situ labelling and genetic tracking the fate of c-kit positive cardiac stem AS 2034178 and the replacement of the eCSC
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The identification of new stem cell
2018-11-08
The identification of new stem cell markers characteristic of a phenotypic subset or experimental state remains a major candesartan cilexetil research goal. Researchers may wish to assess the uniqueness of an expression profile before embarking on experiments that rely on a reporter gene or antibod
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br Materials and methods br Results br Discussion Our result
2018-11-08
Materials and methods Results Discussion Our results show the potential of H2A.Z to provide a highly specific biomarker for identifying purchase congo red in tissues that are undergoing two tightly linked processes, deterministic asymmetric self-renewal and non-random segregation (Rambhatl
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Digoxigenin-11-UTP br Introduction Foundational cell fate re
2018-11-08
Introduction Foundational cell fate reprogramming studies revealed ectopic expression of pluripotency-associated transcription factors (TF) OCT4, SOX2, KLF4, and c-MYC (OSKM) or OCT4, SOX2, NANOG, LIN28 (OSNL) in human fibroblasts (hFibs) cultured in pluripotent supportive conditions was sufficie
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The occurrence of airway epithelial thickening
2018-11-08
The occurrence of airway epithelial thickening in ppar pathway leads to a decrease in airway lumen size, consequently resulting in increased airway resistance corresponding to AHR (Elias, Zhu, Chupp, and Homer, 1999). Data from pediatric and non-fatal asthma studies have shown epithelial thickness
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br Resource table Resource details The
2018-11-08
Resource table. Resource details The study was approved by the Singhealth ethics committee (protocol number SHSIBC-2014-031), and written informed consent was obtained from the patient. 2ml of peripheral blood sample was obtained from a male 64-year-old Parkinson\'s disease patient carrying a h
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It has been hypothesized that
2018-11-08
It has been hypothesized that neurogenesis in DG may play an important role in learning and memory and especially in spatial memory (Deng et al., 2010; Jessberger et al., 2009; Piatti et al., 2013). In the present study, mice with AQ treatment showed an increased percentage of spontaneous alternatio
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In the current work we have attempted to address
2018-11-08
In the current work, we have attempted to address these issues. First, we have successfully generated of iPSCs from USCs, the imidazoline receptors that were derived from patients\' urine, using an integration-free reprogramming protocol. In this protocol, reprogramming factors OSKM were delivered
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br Experimental Procedures br Author Contributions br
2018-11-08
Experimental Procedures Author Contributions Acknowledgments Introduction The defining features of pluripotent stem rotenone (PSCs), whether they originate from germ cell tumors, from the embryo, or through cellular reprogramming, are their abilities to undergo self-renewal and to give
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br Materials and methods br Acknowledgements
2018-11-08
Materials and methods Acknowledgements This work was supported by grants from Instituto de Salud Carlos III (PI 15/000227 to MC, Plataforma en Red de Recursos Biomoleculares y BioinformaticosPRB2 PT13/0001/0042) cofunded by FEDER. Resource table. Resource details Loss-of-function mutation
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The Bag KO mESC line maintains a
2018-11-08
The Bag1KO-mESC line maintains a classical dome-shaped ES cell morphology and expressed high levels of ES-associated protein such as, alkaline phosphatase (Fig. 1D). Immunofluorescent staining for the three key pluripotent stem cell markers Oct4, Sox2 and Nanog revealed that the Bag1KO-mESC line was
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Cisplatin and Vorinostat alone produced exciting results but
2018-11-08
Cisplatin and Vorinostat alone produced exciting results, but their combination was extremely efficient in disrupting CSCs and non-CSCs. After 5days of combined therapy, CSCs were completely depleted in HACC2A cells, and a 3.9-fold reduction in CSCs occurred in HACC6 nk1 antagonist (Fig. 4A and B).
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