• br Materials and methods br Results br Discussion Obesity re

  2018-11-12

  

  Materials and methods Results Discussion Obesity results when caloric intake exceeds energy expenditure, with an increase in adipocyte size or adipocyte number (Bjorntorp, 1974; Faust et al., 1978; Johnson et al., 1971, 1978; Yu et al., 1997). In the context of adipogenesis, development app

• br Materials and methods br Results br Discussion Obesity re

  2018-11-12

  

  Materials and methods Results Discussion Obesity results when caloric intake exceeds energy expenditure, with an increase in adipocyte size or adipocyte number (Bjorntorp, 1974; Faust et al., 1978; Johnson et al., 1971, 1978; Yu et al., 1997). In the context of adipogenesis, development app

• Introduction The degree to which embryonic stem cells ESCs r

  2018-11-12

  

  Introduction The degree to which embryonic stem peptide receptors (ESCs) represent generic properties of pluripotent founder cells in mammalian embryos is unresolved (Nichols and Smith, 2012; Smith, 2001). Mouse ESCs are the paradigmatic model. However, it is increasingly clear that there are diff

• It is interesting to note that the commonly used hBMSC

  2018-11-12

  

  It is interesting to note that the commonly used hBMSC and hMSC marker, CD166, showed a higher expression in osteogenically differentiated tsa inhibitor compared with undifferentiated cells. This increase in expression was also recently demonstrated in hBMSCs undergoing both osteogenic and adipogeni

• Acknowledgments We are indebted to the Citomics unit of the

  2018-11-12

  

  Acknowledgments We are indebted to the Citomics unit of the IDIBAPS for technical help. This work was supported by grants from the Spanish Ministry of Economia y CompetitividadBIO2011-30299-C02-02 and from CIDEM-Generalitat de CatalunyaVALTEC09-2-0047. and was developed at the Centro Esther Koplowi

• br Materials and methods br Results br Discussion In these

  2018-11-12

  

  Materials and methods Results Discussion In these experiments, we sought to determine the influence of gravitational mechanical unloading on the regenerative ability of bone marrow progenitors and specifically hypothesized that exposure to microgravity may alter the differentiation of bone

• Pluripotency tests included flow cytometry analysis of prote

  2018-11-12

  

  Pluripotency tests included flow cytometry analysis of protein stem cell markers SSEA3, SSEA4, Tra1-60, Tra1-81 and Oct3/4 (Fig. 2A), alkaline phosphatase staining (ALP) (Fig. 2B), and qRT-PCR analysis of endogenous pluripotent transcription factors OCT-4, SOX-2, NANOG and REX1 (Fig. 2C). To finally

• DNA fragmentation is an essential component of PCD

  2018-11-12

  

  DNA fragmentation is an essential component of PCD. Of several nucleases that were tested for their involvement in charontosis, EndoG emerged as a likely candidate, although a role for CAD cannot be discounted due to the degradation of ICAD observed 44 h after ETO treatment. EndoG is activated in BM

• br Materials and methods The PQ embryos

  2018-11-12

  

  Materials and methods The PQ embryos from in vitro fertilization were donated, and the fetal membranes were collected in accord with the INPER Ethics Committee (212250-21071) as well as the Guidelines for the Conduct of hESC Research (ISSCR, 2006). The hAEC were isolated and cultured from human

• Our experiments suggest that Runx may be

  2018-11-12

  

  Our experiments suggest that Runx1 may be a useful target to manipulate in order to direct the endogenous NSPC proliferative response toward maximal neurogenesis following traumatic Tenovin-6 injury. Runx1 over-expression has been demonstrated to facilitate neuronal differentiation and long-range a

• br Author contributions br Competing financial interests br

  2018-11-12

  

  Author contributions Competing financial interests Acknowledgments We thank Dr. Sravan K. Goparaju for critical reading our manuscript. This work was supported in part by JSPS KAKENHI (23500446) and the iCeMS exploratory grant for junior investigators to KA. TI was supported in part by the

• To gain insight into the role

  2018-11-09

  

  To gain insight into the role of FA proteins during development and understand the origin of HSPC deficits, we recently investigated fetal hematopoietic function in a murine model of FA, observing quantitative hematopoietic deficits at embryonic day 14.5 (E14.5) (Kamimae-Lanning et al., 2013). This

• Although the mechanisms of in vitro postovulatory

  2018-11-09

  

  Although the mechanisms of in vitro postovulatory aging and in vivo reproductive aging differ, there are some remarkable cytological similarities relevant to human reproduction. It has been reported that aging of human and mouse oocytes can result in disorganization of the spindle and defects in chr

• Accumulating evidence indicates that treatment using extrace

  2018-11-09

  

  Accumulating evidence indicates that treatment using extracellular vesicles (EVs) have multiple advantages over cell therapy, because EVs are stable in the circulation without losing function and exhibit a superior safety profile (Vader et al., 2016). In particular, MSCs are an attractive source of

• Other parameters listed in the

  2018-11-09

  

  Other parameters, listed in the table, describe the so-called dechanneling length [1], i.e. the average distance traveled by a positron in channeling mode. The parameter is defined as the average distance traveled by a trapped particle from entering the crystal until exiting the channel. In other w

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