• KPT-185 br Conflict of interest br Introduction br

  2019-05-13

  

  Conflict of interest Introduction Case report Discussion Dextrocardia is commonly associated with situs inversus totalis (incidence: 2 in 10,000 individuals) and rarely associated with situs solitus (incidence: 1 in 20,000 individuals). While associated cardiac anomalies are seen in appr

• To raise awareness of the importance of birth

  2019-05-13

  

  To raise awareness of the importance of birth registration and to discuss strategies to promote it, UNICEF is launching two related publications on the anniversary of the organisation\'s founding is a statistical analysis spanning 161 countries and presenting the latest available country data and es

• br Discovery of S PR as a CBA sensor

  2019-05-13

  

  Discovery of S1PR2 as a CBA sensor in the liver Early studies reported that activation of the ERK1/2 and AKT signaling pathways by CBAs was PTX-sensitive, suggesting a role for a Gαi-linked GPCR. To identify which GPCR activates the ERK1/2 and AKT signaling pathways, the cDNAs encoding more than

• An urgent need therefore exists for ministries

  2019-05-13

  

  An urgent need therefore exists for ministries of health to introduce programmes for the primary and secondary prevention of rheumatic caffeic acid disease through their non-communicable disease programmes. The delivery of penicillin for the treatment of sore throat in children and the prevention o

• For most health care professionals

  2019-05-13

  

  For most health-care professionals, infectious-disease modelling is something of a black box. One can see the input assumptions (ie, what goes in) and the outputs (ie, what comes out), but what happens in between seems close to magic. Given their complexity, to understand any one of the models used

• br Discussion In our patient

  2019-05-13

  

  Discussion In our patient series, coronary angiography was performed routinely prior to electrophysiological study, revealing a 9.1% (5/55) incidence of significant coronary artery stenosis in patients with Brugada syndrome/Brugada-type ECG. Although acute myocardial ischemia has been reported to

• Introduction Atrial fibrillation AF is the most common

  2019-05-13

  

  Introduction Atrial fibrillation (AF) is the most common arrhythmia in adults and the most common cause of embolic stroke. AF affects approximately 0.8 million patients in Japan alone, and its incidence is expected to grow exponentially [1–3]. However, the electrophysiological mechanisms of the ini

• Introduction Ewing s sarcoma ES is a

  2019-05-10

  

  Introduction Ewing\'s sarcoma (ES) is a high-grade neoplasm representing the second most common primary bone malignancy in both children and adults. With a peak incidence at 15 years, this disease accounts for 2% of childhood cancers [1–3]. ES is defined as a bone tumor which may occur at any site

• br Future perspectives Identification of LOX as a

  2019-05-10

  

  Future perspectives Identification of LOX as a modulator of the ECM to form pre-metastatic niches and subsequently bone metastasis arose as we were investigating the hypoxia tumour secretome using existing patient cohort data and cutting edge proteomics. Although condoned by some researchers as “

• In a recent study Nademanee et

  2019-05-10

  

  In a recent study, Nademanee et al. [76]. reported additional evidence pointing to pathologic changes in the RVOT of patients with BrS that have proved undetectable by echocardiography or MRI. In contrast, imaging techniques in ARVC clearly display morphologic and functional changes (e.g., dilation

• La pol tica institucionalizada se convirti y se

  2019-05-10

  

  La política institucionalizada se convirtió y se aceptó, por parte de los actores relevantes del sistema (neo-oligarquías e instituciones), y en gran medida por lo benevolente y bondadosa que sería para los intereses del gran capital, como el vehículo hacia el futuro del Estado. Se decretó que la cr

• Interpretation Stakeholders from sectors not historically en

  2019-05-10

  

  Interpretation Stakeholders from sectors not historically engaged in health care are forming unique partnerships with common goals and a willingness to address the challenge of global cancer care. Funding None. Declaration of interests Abstract Background Since 2013 medical students from North

• br Case A year old man was referred

  2019-05-09

  

  Case A 45-year-old man was referred for the management of sudden-onset tachycardia. He had experienced 3 episodes of palpitation attacks, lasting for a couple of hours each, during the last 6 months. A regular, wide QRS complex tachycardia (WCT) at 150beats/min with a prominent retrograde P wave

• br To see how the quantity of osteosarcoma

  2019-05-09

  

  To see how the quantity of osteosarcoma in vitro studies developed overtime, we set out to systematically identify all the drugs that have been tested on osteosarcoma BMI-1 inhibitor in vitro in the past two decades. A PubMed search strategy was compiled which can be found in Supplementary data 1

• Automated template matching available in some electrophysiol

  2019-05-09

  

  Automated template matching, available in some electrophysiology systems, has been used to improve pace matching in the ventricle [13]. We found that using automated analysis improved the resolution of pace mapping, especially with bipolar EGMs. The matching algorithms are relatively simple and not

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