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br Discussion CML was the first malignancy to
2019-05-08
Discussion CML was the first malignancy to be linked to a clear genetic abnormality, the Philadelphia chromosome. This chromosomal abnormality is so named because of the city in which it was first discovered and described in 1960 by Peter Nowell and David Hungerford [1]. The fusion protein result
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br Antimicrobial drugs are the most counterfeit or substanda
2019-05-08
Antimicrobial drugs are the most counterfeit or substandard drugs worldwide. The pharmacopoeial quality of these drugs in China is of special concern because China is the second producer, after India, of most counterfeit or substandard drugs in the global market. The antimicrobials circulating in
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HBV DNA levels are associated with clinically significant
2019-05-08
HBV DNA levels are associated with clinically significant pathological events, such as cirrhosis; therefore, changes in the serum levels of HBV DNA could determine a risk for hepatocellular carcinoma. For on-treatment follow-up, HBeAg loss/seroconversion is important during the nucleoside therapy fo
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The goals are set the targets laid out The fighting
2019-05-08
The goals are set; the targets laid out. The fighting is over. In just over a week\'s time, heads of state worldwide will commit to the , with its 17 Sustainable Development Goals (SDGs) and 169 associated targets. Country representatives will resolve to do everything from ending poverty and hunger
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br es resultado de una larga
2019-05-08
es resultado de una larga investigación de la obra de Juan Rulfo, pero es asimismo el fruto de largas reflexiones sobre “el arte de narrar” en general y sobre las relaciones que la literatura entabla con la cultura y la historia en que se inscribe, conexiones ellas mismas históricas. Desde el artí
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Lo que Jos Enrique Rod teoriz en Ariel Vasconcelos de
2019-05-08
Lo que José Enrique Rodó teorizó en Ariel, Vasconcelos, de niño en la escuela de Eagle Pass, pareció vivirlo en carne propia. En esta pelea “escuelera”, asociemos, ¿se asumía Vasconcelos Phos-tag Acrylamide sí mismo como un Ariel, mientras a Jim, el gringo sanguíneo, lo consideraba como un Calibán?
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La pol tica institucionalizada se convirti y se acept
2019-05-08
La política institucionalizada se convirtió y se aceptó, por parte de los actores relevantes del sistema (neo-oligarquías e instituciones), y en gran medida por lo benevolente y bondadosa que sería para los intereses del gran capital, como el vehículo hacia el futuro del Estado. Se decretó que la cr
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A Framework Convention on Global Health FCGH
2019-05-08
A Framework Convention on Global Health (FCGH)—supported by civil society and global leaders—should become the centrepiece of this endeavour (). It would reform global governance for health to enhance accountability, transparency, and civil society participation and protect the right to health in tr
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Reframing non communicable diseases NCDs to
2019-05-08
Reframing non-communicable diseases (NCDs) to “spur a sense of urgency” and “focus attention on effective system-wide interventions” makes sense. With almost three-quarters of NCD deaths now occurring in low-income and middle-income countries (LMICs), the increasing burden of NCDs already has severe
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glycosylase The aim of this study was
2019-05-08
The aim of this study was to determine the therapeutic relevance of blocking RANKL in Ewing\'s sarcoma by using OPG administered by non-viral gene transfer approaches in two models of human Ewing sarcoma in immunodeficient mice. OPG was administered using amphiphilic polymers constituted by blocks o
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caged compounds The Millennium Development Goals MDGs have
2019-05-07
The Millennium Development Goals (MDGs) have become key targets for the international caged compounds over the past 15 years. The MDGs have raised awareness, focused global efforts on agreed priorities, and empowered so-called development champions at country level. This progress was less straightf
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El proceso hist rico de
2019-05-07
El proceso histórico de conformación del Estado en Chile, su momento constitutivo en el siglo xix es precisamente la invasión del Estado liberal chileno a territorio de los pueblos originarios; desposesión que disocia la comunidad cultural mapuche de la soberanía territorial que hasta ese momento ha
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br Ogolpe militar do dia de setembro de
2019-05-07
Ogolpe militar do dia 11 de setembro de 1973, no Chile, destituiu do poder o então presidente Salvador Allende, eleito em 1970 pela Unidad Popular (up), coalizão política composta por partidos de esquerda que propunham erbb2 inhibitor “via chilena para o socialismo”. De acordo com Priscila Carlos
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br La profesionalizaci n del poeta como un
2019-05-07
La profesionalización del poeta como un perfil creador La oferta sin precedentes que se ha experimentado en el terreno poético luego de varias iniciativas editoriales públicas y privadas en los años 1980-2010 (por ejemplo, Gabriel Bernal Granados o León Plascencia Ñol: 235) ha generado una bonanz
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The beats with high amplitude
2019-05-07
The beats with high-amplitude J wave with short preceding DIs induced low systolic blood pressure, indicating weak cardiac contractility due to decreased calcium influx through I and calcium release during ventricular systole. In contrast, the beats with low-amplitude J wave preceded by long DIs ind
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