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In an earlier study we used
2019-06-18
In an earlier study, we used a questionnaire to assess musculoskeletal pain in patients with CML who had achieved DMR (MR4.0) and discontinued TKI treatment, including IM, nilotinib, and dasatinib [5]. Nine out of the 27 patients surveyed developed musculoskeletal pain after discontinuing TKIs. In t
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We also found that the RBC folate
2019-06-18
We also found that the RBC folate level was significantly increased in individuals with the TT purchase G-1 compared to individuals with the CC genotype. The plasma folate concentration fluctuates in relation to diet, and is thus a useful dynamic measure that reflects recent nutritional uptake. Ther
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T wave alternans is a
2019-06-18
T-wave alternans is a periodic beat-to-beat variation in the amplitude or morphology of the T wave on electrocardiography (ECG) (Fig. 1). Beat-to-beat T-wave alternans is considered to reflect increased dispersion of ventricular repolarization, and it is known to often precede the development of let
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br Monitoring coagulation levels Coagulation levels can be m
2019-06-18
Monitoring coagulation levels Coagulation levels can be monitored after warfarin treatment by measuring the prothrombin time (PT). However, monitoring is not needed for novel anticoagulants because these drugs have a much wider therapeutic range than warfarin. Nonetheless, in patients at high ris
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br Methods br Results br Discussion Bisphosphonates
2019-06-18
Methods Results Discussion Bisphosphonates reduce skeletal morbidity in patients with advanced cancers involving bone and have become a recommended component of the multidisciplinary treatment of MBD [1]. However, bone-health benefits have not generally translated into significantly improve
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Early repolarization ER is characterized by elevation
2019-06-18
Early repolarization (ER) is characterized by elevation of the QRS-ST junction (J point) and QRS notching or slurring (J wave) in multiple leads, especially the inferior and/or left precordial leads. Although this finding has been considered to be a benign ECG manifestation, Haïssaguerre et al repor
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2-NBDG Las l neas le comunican a Felipe que l
2019-06-18
Las líneas le comunican 2-NBDG Felipe que él y sus marañones habían determinado salir De lo primero, denuncia la perversidad de la administración, encabezada por el virrey Cañete, “malo, lujurioso, ambicioso tirano”, quien “premió” a los hombres que combatieron la rebelión de Hernández Girón con pe
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buy Cordycepin HBeAg positive patients older than years with
2019-06-18
HBeAg-positive patients older than 40 years with persistently high or high to normal ALT levels may be diagnosed with significant hepatic necroinflammation or fibrosis. During treatment, the clinical significance of timing of HBeAg loss or seroconversion remains unclear. However, a longer duration o
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HF is associated with the
2019-06-18
HF is associated with the down-regulation of multiple potassium (K) currents (i.e., Ito, IKs, IKr, IK1, and IKATP). The only K channel that is upregulated in HF is the small conductance Ca-activated K (SK) channel. The SK channel was originally found in most neurons. The increase in Cai evoked by th
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We observed a downregulation of
2019-06-17
We observed a downregulation of several thyroid-related genes such as DUOX1, DUOX2, TG, and TSHR. This may appear counterintuitive given that dedifferentiation typically worsens patient outcomes. However, it is noteworthy that there was no difference in the SC 560 of SLC5A5 (sodium-iodide symporter
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br Conclusions It is now clear that a
2019-06-17
Conclusions It is now clear that a number of CD 2665 cost are involved in inherited bradyarrhythmia. Recent genetic studies have demonstrated that inherited arrhythmia is attributable to many genes with diverse functions. While the precise underlying mechanisms remain to be elucidated; these gen
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The district specific estimates of effectiveness figure incl
2019-06-17
The district-specific estimates of effectiveness (figure 1) include infections averted in all population subgroups over the first 4 years, even for districts without surveys of men who have sex with men and the general population, and the state-level and overall proportion of infections averted acro
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Sazonov recuerda el viejo debate
2019-06-17
Sazonov recuerda el viejo debate sobre las fuentes del pensamiento revolucionario, y pasa lista TCS JNK 5a las fuentes propuestas por las diferentes escuelas: la Biblia y el cristianismo, la Revolución francesa y el mundo ilustrado, el republicanismo clásico, el pensamiento renacentista. Todas ellas
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The clinical spectrum of intracranial hemorrhage is
2019-06-17
The clinical spectrum of intracranial hemorrhage is similar for patients treated with warfarin and dabigatran [10]. Absolute rates of intracranial hemorrhage across all sites and of both fatal and traumatic intracranial hemorrhages are lower with dabigatran than with warfarin [10]. Concomitant aspir
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LQTS is classified into subtypes LQT
2019-06-17
LQTS is classified into subtypes LQT1 to LQT13 based on the site of genetic mutation. Each type possesses distinct clinical characteristics and a different prognosis. Treatment choice depends partly on individual phenotype and partly on genotype. Among Asian countries, several reports have been publ
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