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Many investigators participated in the studies on
2019-11-15
Many investigators participated in the studies on the regulation of the kn to nm and experiments indicated that the process was conserved across many eukaryotic species including humans [127]. Because cancer cells exhibit dysregulated cell division along with the presence of abnormal chromosome num
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AM251 In the SUMOylation pathway SCE as an E
2019-11-14
In the SUMOylation pathway, SCE1 as an E2 enzyme has an important role in mediating the conjugation of SUMO to target proteins. The accumulated SUMO conjugates in plants are associated with abiotic stress responses (Castro et al, 2012). We performed a drought stress analysis on WT plants, induced by
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The human serotonin hydroxytryptamine HT
2019-11-14
The human serotonin (5-hydroxytryptamine; 5-HT) receptor family consists of 14 receptor subtypes to date, which are primarily G protein-coupled receptors (GPCRs) with 5-HT3 being the sole ligand-gated ion channel (Alexander et al., 2017). These receptors are widely distributed in the central and per
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We demonstrated that cells expressing less DHODH were
2019-11-14
We demonstrated that Combretastatin A4 expressing less DHODH were less sensitive to DHODH inhibitors regardless of their oncogenic status. Based on the proliferation speed of cells, Kant et al. (1989), showed that slow-growing squamous cell carcinoma was more sensitive to BQR than fast-growing muri
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Two key enzymes play important roles in
2019-11-14
Two key enzymes play important roles in the bioconversion of xylitol from d-arabitol, namely d-arabitol dehydrogenase (ArDH) and NADH-dependent xylitol dehydrogenase (XDH), respectively (Qi et al., 2014). In an earlier study, we developed a high xylitol yield strain by expressing xdh in E. coli BL21
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br DDR in atherosclerosis and vascular
2019-11-14
DDR1 in atherosclerosis and vascular disease The Canadian group of Bendeck, explored the role of DDR1 in repair following arterial injury in rats [30]. DDR1 protein levels, assessed via Western blots prepared from arterial extracts taken at various times after injury, showed DDR1 protein dramatic
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Research done thus far supports the hypothesis
2019-11-14
Research done thus far supports the hypothesis that MPA has detrimental effects on cognition, alone and in combination with estrogen; there are other FDA-approved progestogens that satisfy the uterus opposing effects that have not been cognitively profiled. An important goal to aid women\'s health i
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Enzyme selectivity of many enzymes like galactosidases acyla
2019-11-14
Enzyme selectivity of many X-NeuNAc mg like β-galactosidases, acylases, epoxyhydrolases, lipases, etc. has also been modulated by using different immobilization techniques. It can result in the selection of optimal biocatalyst for different processes. This has many advantages over strategies like ge
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br Introduction Hydrogen sulfide H
2019-11-14
Introduction Hydrogen sulfide (H2S) and nitric oxide (NO) are important gasotransmitters in the cardiovascular system and instrumental to the fine control of vascular tone [1] and cellular function [2]. NO is synthesized from l-arginine by calmodulin-dependent endothelial nitric oxide synthase (e
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However in many of the
2019-11-14
However, in many of the above mentioned studies, the NaCl concentrations in the extraction buffers were different from those used here. For instance, in the study that performed cathepsin D extraction from human AD Varenicline Tartrate receptor tissue, the concentration was 150mM [30], while that fo
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br Results This study was carried out with
2019-11-13
Results This study was carried out with a series of engineered extracellular matrix films of collagen assembled at hydrophobic surfaces, which allow for independent control of supramolecular structure, mechanical stiffness, and receptor recognition sites [17], [21]. Vascular smooth muscle cytocha
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Based on the ability of
2019-11-13
Based on the ability of CRF to modulate nociception, we hypothesized that stress leads to hyperalgesia by the activation of CRF1 and/or CRF2 receptors in the spinal cord. We tested this hypothesis using an acute forced swim as a widely used and easily reproducible stressor and grip force as a measur
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The regression also revealed a
2019-11-13
The regression also revealed a significant association between admission selectivity (SELECT) and exam pass rate (PASS%) (p ctep serve as an indicator of a student’s ability to learn and their aptitude for academic success. These same qualities likely enable more selective schools to design more rig
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The distorted geography on the number lines of many pre
2019-11-13
The distorted geography on the number lines of many pre-service primary teachers in this study also highlights the need to provide them with strong visual models of negative numbers and their ordering. The evidence from Indri\'s interview is that some standard models of negative numbers (e.g., lendi
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br Using the same sort of
2019-11-13
Using the same sort of methods, we can also address the proof of Theorem 1.2. The first part of the proof is made much easier if we use the “sieving” construction. Concretely, given a CMV operator , let denote the CMV operator with This induces a simple change in the spectrum; namely, if denotes
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