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br Acknowledgements This work was
2020-06-02
Acknowledgements This work was supported in part by JSPS KAKENHI Grant Number 26292031. Introduction The Cys-loop receptors constitute an important superfamily of ligand-gated ion Irsogladine synthesis (LGICs) and mediate synaptic transmission in both invertebrate and vertebrate nervous syst
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DLPC In contrast to drospirenone dydrogestrone acts rather n
2020-06-02
In DLPC to drospirenone dydrogestrone acts rather neutral at the aldosterone-, glucocorticoid- and androgen-receptor [12]. This indicates that the assessment of a ‘net-overall effect’ on the vascular system is very difficult based on the often discussed ‘partial effects’ of the progestogens. Thus, c
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br ANTITHROMBOTIC TREATMENTS br VOLUME OUTCOME RELATIONSHIP
2020-06-02
ANTITHROMBOTIC TREATMENTS VOLUME-OUTCOME RELATIONSHIP FOR REVASCULARIZATION PROCEDURES The guidelines also maintain the recommendations for training in PCI, both for ACS (≥ 75 procedures per operator in centers with at least 400 PCI procedures per year and a 24-hour on-call service) and for st
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br Materials and methods br Results br
2020-06-02
Materials and methods Results Discussion Studies have suggested that the Hh signaling pathway, which plays as an essential autocrine viability factor for MFBs [10], [11], is a potential therapeutic target for liver fibrosis. Previously reported works have proven the effectiveness of the Hh
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br Materials and methods br
2020-06-01
Materials and methods Results As shown in Table 1, blood urea nitrogen and serum creatinine levels were significantly elevated at both 1st and 7th days of pyelonephritis, when compared with those of the control group (Popioid receptors formation or intratubular neutrophils, while tubules show
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Confidence with which data of animal safety toxicity
2020-06-01
Confidence with which data of animal safety/toxicity studies can be translated to human depends upon the knowledge that whether humans would be exposed to similar chemical entities (parent and its metabolites) as the animals exposed during toxicity studies. In this regard, in vitro qualitative evalu
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Carnitine acetyltransferase CrAT transesterifies short chain
2020-06-01
Carnitine acetyltransferase (CrAT) transesterifies short-chain acyl-CoAs, and is located both in mitochondria and peroxisomes. In yeasts and mammals this protein is the product of a single gene [20,21] and the sorting to different organelles is evolutionary conserved, although the mechanism of diffe
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Cryoprotectant equilibration and the response to ice
2020-06-01
Cryoprotectant equilibration and the response to ice concentrated media are the two facets of cellular cryobiological protocols most commonly covered by mathematical modeling. In these models, NS 1619 sale are typically assumed to have uniform, spatially independent extracellular concentrations and
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Kim et al reported for bioactive compounds originating from
2020-06-01
Kim et al. reported for bioactive compounds originating from the endemic species in Korea, the hexane and EtOAc fractions of the MeOH extracts from the roots of Dystaenia takeshimana (Nakai) Kitagawa (Umbelliferae) showed cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) dual inhibitory activity b
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Many researchers studied the experimental investigation of
2020-06-01
Many researchers studied the experimental investigation of RHA in cement enhances the strength and durability of the concrete [9], [10], [11], [12]. It is most important that concrete must withstand its strength even after it is being exposed to any corrosive environment over a period of time. In ad
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Introduction Piperine is a pungent alkaloid
2020-05-29
Introduction Piperine is a pungent alkaloid and accounts for 2–5% dry weight in black and white peppers (Butt et al., 2013). Physiological benefits of piperine have been a subject of extensive research in recent years. Piperine is an antioxidant with strong anti-inflammatory and antiangiogenic acti
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Being a rare renal tumor its description as primary renal
2020-05-29
Being a rare renal tumor, its description as primary renal tumor has been confined to the documentation of anecdotal case reports in the past [4], [9], [10], [11]. However, recent years have seen an increased interest in defining ES/PNET of kidney as a distinct entity, with the study undertaken by t
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br Conclusion br Acknowledgments This work
2020-05-29
Conclusion Acknowledgments This work was supported by Progetto PON - “Ricerca e Competitività 2007–2013” - PON01_01802: “Sviluppo di molecole capaci di modulare vie metaboliche intracellulari redox-sensibili per la prevenzione e la cura di patologie infettive, tumorali, neurodegenerative e lor
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Several DA receptors heteromers with
2020-05-29
Several DA receptors heteromers with a therapeutic potential have been described, including D1R/D3R (Fiorentini et al., 2010), but their roles remain to be established. Moreover, most studies on receptor heteromers in addiction focused on the striatum because of its key role in the pathology and its
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Organometallic compounds exhibited remarkable potential for
2020-05-29
Organometallic compounds exhibited remarkable potential for the development of new cancer drugs not only due to the direct cytotoxicity but also to the drug targeting and active anticancer immune response ability [4]. Among the organometallic compounds, ferrocene is one of the most well-known compou
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