• br Materials and methods br Results br Discussion In these

  2018-11-12

  

  Materials and methods Results Discussion In these experiments, we sought to determine the influence of gravitational mechanical unloading on the regenerative ability of bone marrow progenitors and specifically hypothesized that exposure to microgravity may alter the differentiation of bone

• Pluripotency tests included flow cytometry analysis of prote

  2018-11-12

  

  Pluripotency tests included flow cytometry analysis of protein stem cell markers SSEA3, SSEA4, Tra1-60, Tra1-81 and Oct3/4 (Fig. 2A), alkaline phosphatase staining (ALP) (Fig. 2B), and qRT-PCR analysis of endogenous pluripotent transcription factors OCT-4, SOX-2, NANOG and REX1 (Fig. 2C). To finally

• DNA fragmentation is an essential component of PCD

  2018-11-12

  

  DNA fragmentation is an essential component of PCD. Of several nucleases that were tested for their involvement in charontosis, EndoG emerged as a likely candidate, although a role for CAD cannot be discounted due to the degradation of ICAD observed 44 h after ETO treatment. EndoG is activated in BM

• br Materials and methods The PQ embryos

  2018-11-12

  

  Materials and methods The PQ embryos from in vitro fertilization were donated, and the fetal membranes were collected in accord with the INPER Ethics Committee (212250-21071) as well as the Guidelines for the Conduct of hESC Research (ISSCR, 2006). The hAEC were isolated and cultured from human

• Our experiments suggest that Runx may be

  2018-11-12

  

  Our experiments suggest that Runx1 may be a useful target to manipulate in order to direct the endogenous NSPC proliferative response toward maximal neurogenesis following traumatic Tenovin-6 injury. Runx1 over-expression has been demonstrated to facilitate neuronal differentiation and long-range a

• br Author contributions br Competing financial interests br

  2018-11-12

  

  Author contributions Competing financial interests Acknowledgments We thank Dr. Sravan K. Goparaju for critical reading our manuscript. This work was supported in part by JSPS KAKENHI (23500446) and the iCeMS exploratory grant for junior investigators to KA. TI was supported in part by the

• To gain insight into the role

  2018-11-09

  

  To gain insight into the role of FA proteins during development and understand the origin of HSPC deficits, we recently investigated fetal hematopoietic function in a murine model of FA, observing quantitative hematopoietic deficits at embryonic day 14.5 (E14.5) (Kamimae-Lanning et al., 2013). This

• Although the mechanisms of in vitro postovulatory

  2018-11-09

  

  Although the mechanisms of in vitro postovulatory aging and in vivo reproductive aging differ, there are some remarkable cytological similarities relevant to human reproduction. It has been reported that aging of human and mouse oocytes can result in disorganization of the spindle and defects in chr

• Accumulating evidence indicates that treatment using extrace

  2018-11-09

  

  Accumulating evidence indicates that treatment using extracellular vesicles (EVs) have multiple advantages over cell therapy, because EVs are stable in the circulation without losing function and exhibit a superior safety profile (Vader et al., 2016). In particular, MSCs are an attractive source of

• Other parameters listed in the

  2018-11-09

  

  Other parameters, listed in the table, describe the so-called dechanneling length [1], i.e. the average distance traveled by a positron in channeling mode. The parameter is defined as the average distance traveled by a trapped particle from entering the crystal until exiting the channel. In other w

• The acoustically opaque hood for the MF

  2018-11-09

  

  The acoustically opaque hood for the MF (Fig. 3) was made in the shape of the dolphin\'s rostrum and was snugly fit over it. The length of the hood was about 15cm. It was made from a 5 mm-thick sheet of neoprene foam with closed pores. This material has a high strength and high water and oil resista

• Fig also shows the theoretical

  2018-11-09

  

  Fig. 3 also shows the theoretical dependences of the phosphatidylinositol 4-kinase of the allowed transitions on the width of InGaAsSb/AlGaAsSb quantum wells at liquid nitrogen temperature. The dash-dot line 1 corresponds to the calculated energy of the transitions between the ground state of heavy

• Marketing literature states that a beneficial

  2018-11-09

  

  Marketing literature states that a beneficial or successful m-CRM can be influenced by different company resources, such as technological, economic, and human ones (e.g. employees and managers), as well as by its capacity and/or competence (Sarmaniotis, Assimakopoulos, & Papaioannou, 2013). Accordin

• We did not find any difference in

  2018-11-09

  

  We did not find any difference in the percent of NBC infected with low or high MOI by IFA or RT-PCR. ZIKV could potentially use DC-SIGN and phosphatidylserine receptors, such as T-cell immunoglobulin and mucin domain (TIM) and TYRO3, AXL, and MER (TAM; Hamel et al., 2015; Meertens et al., 2012), or

• learning pathways HEV may also contribute to various extrahe

  2018-11-09

  

  HEV may also contribute to various extrahepatic manifestations, including pancreatitis, hematological disorders (thrombocytopenia and anemia), kidney disorders and neurological complications (Guillain-Barré syndrome and meningoencephalitis) (Singh and Gangappa, 2007; Thapa et al., 2009; Wedemeyer et

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