• The genotype and allele frequencies of the DFEB G A

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• br Acknowledgments This study was supported by grants from t

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  Acknowledgments This study was supported by grants from the Taiwan National Science Council (99-2314-B-037-007-MY3, 100-2314-B-182A-096-MY3) and Chang Gung Medical Research Program (CMRPG8C0821) and is based in part on the National Health Insurance claim database provided by the Bureau of Nationa

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  Materials and methods Acknowledgements Mef2c-AHF-Cre mice were generously provided by Dr. Brian L. Black. We thank Mamen Martín and Sandra Rodríguez (Molecular Cytogenetics Unit, CNIO) for technical advice; and the Imaging Core Facility for the confocal analysis (CIMA, University of Navarra).

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  Hematopoietic stem UNC 0642 Supplier (HSCs) maintain the turnover of red blood cells, platelets, and immune cells. They reside in the bone marrow, where several cell types contribute to their regulation (Lo Celso et al., 2011; Morrison and Scadden, 2014). How the concerted action of multiple niche c

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  Although inhibition of p38 MAPK signaling prevented spontaneous differentiation of huSCs ex vivo, this effect was reversible. After 2 weeks of expansion in the presence of p38i, the drug was chased for a period of 5 days, during which we observed a significant increase in MYOG expression (Figure S4A

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  Given that a global effort has been initiated to develop donor banks of human leukocyte antigen (HLA)-matched iPSC banks that will serve as an extensive library for selecting close to optimal matches for patients (Turner et al., 2013; Fairchild 2015; Solomon et al., 2015), it is clear that the need

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  FUS binds to DNA as well as to RNA and regulates the expression of many transcripts in multiple steps of the gene regulation process (Dormann and Haass, 2013). In this study, we used FALS MPCs efficiently oriented into neuronal lineages including HB9-positive motor neurons to observe altered gene re

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  Introduction Cardiovascular diseases rank the first in cause of death, which account for ∼30% of all deaths worldwide (Mozaffarian et al., 2015). Unlike robust cardiac regeneration observed in adult zebrafish and embryonic and neonatal mice (Porrello et al., 2011; Poss et al., 2002; Sturzu et al.

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