• Introduction The notorious frontispiece of

  2018-10-22

  

  Introduction The notorious frontispiece of the 1905 edition of A History of Architecture on the Comparative Method, written by the two Banister Fletchers, father and son, and entitled “The Tree of Architecture,” illustrated various style of European architecture emerging out of a trunk labeled “Gre

• The challenge of developing adaptive responsive low energy a

  2018-10-22

  

  The challenge of developing adaptive, responsive low-energy architecture requires new knowledge about the complex and dynamic interaction between envelope geometry and optimisation of performance metrics (Hudson, 2008). In this paper, we present the results of a building envelope tessellation study

• In this work the study of the

  2018-10-22

  

  In this work, the study of the spatial distribution of temperatures in two test trpv1 was based on the concept of the experimental typical day, which represents a specific climate condition according to the Dynamic Climate approach. The possibility of adopting this approach in a short time contribut

• Introduction There is increasing interest in exploring

  2018-10-22

  

  Introduction There is increasing interest in exploring complex freeform shapes in contemporary architectural and design practice. Frank Gehry (Lindsey, 2001) and Zaha Hadid (Jodidio, 2009) are prime examples of pioneering avant-garde designers who have incorporated freeform shapes into their design

• After deployment of the second

  2018-10-22

  

  After deployment of the second SEMS, esophagography (Fig. 3) and bronchoscopy (Fig. 1B) were performed again and showed no signs of TE fistula recurrence. The patient complained of neck pain, but the patient became capable of oral intake again. The patient died 4 months after placement of the second

• br mtDNA mutation in human cancers Several

  2018-10-22

  

  mtDNA mutation in human cancers Several authors have evaluated not only the quantitative change in mtDNA copy number, but also the qualitative mtDNA D-loop mutations in human cancers. D-loop mutations, including the D310 region, have been reported in prostate cancer, head and neck cancer, lung ca

• Introduction An estimated of wastewater in developing countr

  2018-10-22

  

  Introduction An estimated 90% of wastewater in developing countries undergoes no treatment (Corcoran et al., 2010). For example in Kumasi, Ghana, only 8% of the wastewater undergoes some form of treatment (Keraita et al., 2002), while the remaining raw sewage flows to wetlands linked to small strea

• Introduction Rheumatoid arthritis RA is

  2018-10-22

  

  Introduction Rheumatoid arthritis (RA) is a chronic, inflammatory, autoimmune disease, affecting freely movable joints, such as hand, knee and shoulder joints. The symptoms of active RA include pain, swelling, morning stiffness, warmth, redness, and limits in the functions of the joints. The system

• Introduction The intestinal tract of adult carries kg of

  2018-10-22

  

  Introduction The intestinal tract of adult carries 1–2kg of microbes. It is a common knowledge that pathogenic microbes could cause infectious diseases such as diarrheal, while others are associated with inflammatory and allergic diseases [1–3]. On the other hand, the majority of the gut microbes

• Research into embryogenesis and nervous system

  2018-10-22

  

  Research into embryogenesis and nervous system development has been instrumental to the identification of factors required for cell specification. Using information gleaned from these studies, many groups have developed induction protocols to instruct hESCs and iPSCs to become a variety of neural ce

• br Material and methods br Acknowledgment The authors would

  2018-10-22

  

  Material and methods Acknowledgment The authors would like to thank Mr. Chee Peng Ng (Institute of Molecular and Cell Biology, Singapore) for his help on the electron scanning microscope and Dr. William Birch (Institute of Materials Research and Engineering, Singapore) for his critical review

• Therefore a major goal remains to understand the complex cel

  2018-10-22

  

  Therefore, a major goal remains to understand the complex cellular and molecular network that controls HSC generation and expansion. In fact, HSCs that are mainly slow cycling (Wilson et al., 2008) and reside in the bone marrow during the entire life of an individual, are not generated there. They a

• The increasing number of studies focusing

  2018-10-22

  

  The increasing number of studies focusing on regenerative medicine and stem cell transplantation is being accompanied by the development of techniques using many types of nanoparticles. The combination of nanotechnology with stem cell research may be able to address some challenges in this research

• br Results br Discussion In this study

  2018-10-22

  

  Results Discussion In this study, we identified altogether 21 novel imprinted DMRs, including a novel class of intergenic DMRs, which reside in regions with no apparent imprinted ABT-263 in PSCs. This class of imprinted DMRs either may regulate genes in a tissue-specific manner, thus adding t

• PLX-4720 Although our work with BRCA mutant iPSCs

  2018-10-22

  

  Although our work with BRCA1 mutant iPSCs led to our investigation of PKC-theta upregulation in human breast tumors, future studies will be necessary to validate whether PKC-theta can be used as a biomarker or therapeutic target in BRCA1 mutant tumors. Because the frequency of BRCA1 mutations in pat

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